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Clinical Practice Guidelines

One of the main objectives of the ISRS is to elucidate best practices and provide guidance for the safe and effective practice of radiosurgery.During the past several years, a number of important guidelines have been published under the direction of and with input from global experts.  Additional guidelines are in development.    

This Guideline development process reflects a mentorship strategy intended to develop the next generation of leaders in radiosurgery as each project lead is matched with a senior academician.  The ISRS is grateful for the considerable time and effort of each of the contributors.

Most of the following guidelines may be accessed free of charge via open access by clicking on the publication titles.

EXTRACRANIAL

SPINE

REIRRADIATION SPINE STEREOTACTIC BODY RADIATION THERAPY (SBRT) FOR SPINAL METASTASES
Myrehaug S, Sahgal A, Hayashi M, Levivier M, Ma L, Martinez R, Paddick I, Régis J, Ryu S, Slotman B, De Salles A
J Neurosurg Spine. 2017 Jul 14:1-8.
DOI: 10.3171/2017.2.SPINE16976.

STEREOTACTIC BODY RADIOTHERAPY FOR DE NOVO SPINAL METASTASES
Husain ZA, Sahgal A, De Salles A, Funaro M, Glover J, Hayashi M, Hiraoka M, Levivier M, Ma L, Martínez-Alvarez R, Paddick I, Régis J, Slotman BJ, Ryu S
J Neurosurg Spine. 2017 Jun 9:1-8.
DOI: 10.3171/2017.1.SPINE16684

In Development
Post-Op Spine SRS: Salman Faruqui and Antonio De Salles 

 

INTRACRANIAL

BENIGN TUMORS

STEREOTACTIC RADIOSURGERY FOR BENIGN (WORLD HEALTH ORGANIZATION GRADE I) CAVERNOUS SINUS MENINGIOMAS - INTERNATIONAL STEREOTACTIC RADIOSURGERY SOCIETY (ISRS) - PRACTICE GUIDELINE: A SYSTEMATIC REVIEW
Lee CC, Trifiletti DM, Sahgal A, DeSalles A, Fariselli L, Hayashi M, Levivier M, Ma L, Álvarez RM, Paddick I, Regis J, Ryu S, Slotman B, Sheehan J. 
Neurosurgery. 2018 Mar 15.
DOI: 10.1093/neuros/nyy009

VESTIBULAR SCHWANNOMA
Tsao M, Sahgal A, Xu W, De Salles A, Hayashi M, Levivier M, Ma L, Martinez R, Régis J, Ryu S, Slotman B, Paddick I
Journal of radiosurgery and SBRT. 2017 Vol. 5 (1), 5-24.

In Development
Pituitary Tumor (Non-Functional):  Rupesh Kotecha, John Suh and Shoji Yomo
Pituitary Tumor (Secretory): David Mathieu and Jason Sheehan
Non-CS Meningioma: Marcello Marchetti and Laura Fariselli


FUNCTIONAL/EPILEPSY

STEREOTACTIC RADIOSURGERY FOR TRIGEMINAL NEURALGIA
Tuleasca C, Régis J, Sahgal A, De Salles A, Hayashi M, Ma L, Martínez-Alvarez R, Paddick JI, Ryu S, Slotman BJ, Levivier M.
J Neurosurg. 2018 Apr 27:1-25.
DOI: 10.3171/2017.9.JNS17545

STEREOTACTIC RADIOSURGERY FOR TREMOR
Martínez-Moreno N, Sahgal A, De Salles A, Hayashi M, Levivier M, Ma L, Paddick I, Régis J, Ryu S, Slotman B, Martínez-Álvarez R
Journal of Neurosurgery 2018 23(2) 1-12.
DOI: 10.3171/2017.8.JNS17749

GAMMA KNIFE RADIOSURGERY FOR EPILEPSY
McGonigal A, Sahgal A, De Salles A, Hayashi M, Levivier M, Ma L, Martinez R, Paddick I, Ryu S, Slotman B, Régis J
Epilepsy research 2017 Vol 137 123-131.
DOI: 10.1016/j.eplepsyres.2017.08.016


MALIGNANT TUMORS

STEREOTACTIC RADIOSURGERY IN THE MANAGEMENT OF LIMITED BRAIN METASTASES (ONE TO FOUR)
Chao S, De Salles A, Hayashi M, Levivier M, Ma L, Martinez R, Paddick I, Régis J, Ryu S, Slotman B, Sahgal A
Neurosurgery 2017 11(3)
DOI: 10.1093/neuros/nyx522

In Development
Cavity SRS: Kristen Redmond and Arjun Sahgal
Multiple Brain Metastases (>5): Steve Braunstein and Lijun Ma
Technologic Considerations for Metastases: Alexis Dimitriadis and Ian Paddick 


VASCULAR DISORDERS

STEREOTACTIC RADIOSURGERY FOR SPETZLER-MARTIN GRADE I AND II ARTERIOVENOUS MALFORMATIONS: INTERNATIONAL SOCIETY OF STEREOTACTIC RADIOSURGERY (ISRS) PRACTICE GUIDELINE
Graffeo CS, Sahgal A, De Salles A, Fariselli L, Levivier M, Ma L, Paddick I, Regis JM, Sheehan J,Suh J, Yomo S, Pollock BE
Neurosurgery. 2020 Feb 17.
DOI: 10.1093/neuros/nyaa004